Microencapsulation Fluidics System

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1.0 DESCRIPTION This is a Combined Synopsis/Solicitation for commercial products and commercial services conducted in accordance with RFO FAR Part 12, Acquisition of Commercial Products and Commercial Services, using the simplified procedures applicable to commercial products and commercial services. This notice constitutes the solicitation. Quotations are requested, and a separate written solicitation will not be issued. The National Institute of Environmental Health Sciences (NIEHS), Division of Translational Toxicology (DTT), Mechanistic Toxicology Branch (MTB), intends to acquire a commercially available microencapsulation fluidics system, including the required microfluidic modules, pumping and droplet-generation components, computer and software, installation, and training. The Government is seeking a commercially available system that meets the functional, performance, and operational requirements described in the attached Requirements Document. The Government will consider quotations for the named product as well as products offered by other manufacturers that demonstrate compliance with all stated requirements. The Government's requirement is based on the functional and performance characteristics necessary to support the intended scientific application and is not restricted to a particular manufacturer, make, or model. The Government requires a specialized microencapsulation fluidics platform capable of combining liquid-form alginate with human cell suspensions under controlled conditions and generating droplets that form alginate capsules around suspension cells. The system will support the formation of three-dimensional (3D) microtissues, organoids, spheroids, and other advanced cell models for translational toxicology applications. The required system shall provide controlled microfluidic pumping and droplet-generation capabilities suitable for the Government's intended application. The system shall permit reliable and reproducible combination of alginate and human cell suspensions and generation of appropriately sized droplets under controlled operating conditions. The requirement includes the system hardware, applicable control equipment, computer and software necessary for operation, installation, and user training. Installation and training shall be performed at the NIEHS facility and shall include sufficient instruction to enable designated laboratory personnel to operate the system and perform the required microencapsulation procedures. The system shall operate independently of NIEHS information technology systems and shall not require integration with NIEHS enterprise information technology infrastructure. Acceptance shall be based on the Government's determination that the delivered system has been installed and configured in accordance with the solicitation requirements and is capable of performing the specified microencapsulation process. Acceptance may include demonstration of successful formation of alginate-encapsulated human cell-containing microtissues using Government-provided materials. The Government anticipates awarding a firm-fixed-price purchase order to the responsible offeror whose quotation conforms to the solicitation requirements and whose price is determined fair and reasonable. The Government will consider quotations from all responsible sources capable of meeting the complete requirements. An offeror may propose any manufacturer's product or system that meets or exceeds the stated salient physical, functional, and performance characteristics. Required delivery date: September 30, 2026 Delivery Location: NIEHS Rall Building 101, Laboratories E144-146 111 T.W. Alexander Drive Research Triangle Park, NC 27709 The applicable NAICS code is 334516 – Analytical Laboratory Instrument Manufacturing. The applicable PSC is 6630 – Chemical Analysis Instruments. Please see the attached Requirements Document for the detailed technical and performance requirements. Please see the attached…

Lingua di questo bando: English. Titolo e descrizione sono mostrati esattamente come pubblicati dalla stazione appaltante.