EVOS M5000 microscope for monitoring and documenting cultured cell images

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1.0 DESCRIPTION This is a combined synopsis/solicitation for commercial products prepared in accordance with RFO FAR Part 12. This announcement constitutes the only solicitation. Quotations are being requested, and a separate written solicitation will not be issued. Solicitation No. 75N98026Q01227 is issued as a Request for Quotation (RFQ) for EVOS M5000 Microscope for Monitoring and Documenting Cultured Cell Images. The Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Institute of Environmental Health Sciences (NIEHS), intends to procure, on a sole source basis, an EVOS M5000 Imaging System from the manufacturer, Thermo Fisher Scientific. The EVOS M5000 Imaging System is required to support cell imaging and analysis conducted by the laboratory within the National Institute of Environmental Health Sciences (NIEHS). The system will be used to image and analyze cells grown in culture and is a critical component of new and ongoing research projects. The EVOS M5000 Imaging System will replace aging and outdated imaging equipment that no longer meets the laboratory's current requirements for work involving cultured cells. The required system provides the specific combination of capabilities necessary for the laboratory's research, including a compact, fully integrated configuration suitable for use within the laboratory's existing biological safety cabinet (BSC); position tracking for longitudinal monitoring of live cells; integrated quantitative analysis for cell counting, confluence, and transfection/transduction efficiency; and multi-modal imaging of both live cultured cells and fixed or fluorescently stained specimens. The Government intends to procure the EVOS M5000 Imaging System on a sole-source basis from Thermo Fisher Scientific. The required system includes a fully integrated digital inverted microscope capable of four-color fluorescence, transmitted-light, and color imaging; a high-sensitivity 3.2 MP monochrome camera; autofocus; Z-stacking; time-lapse imaging; position-sensing X/Y stage and software-based location tracking; and onboard software for cell imaging and quantitative analysis. The system is required to support cell counting, confluence assessment, and determination of transfection/transduction efficiency and shall be capable of imaging live cells and fixed or fluorescently stained cells in culture vessels and on glass microscope slides. The system shall be sufficiently compact and fully integrated to operate within the laboratory's existing biological safety cabinet. The laboratory conducted market research and evaluated commercially available alternatives to avoid unnecessarily restricting this acquisition to a single manufacturer. Three systems were evaluated, including the Thermo Fisher Scientific EVOS M5000 Imaging System, the ECHO Revolve, and the Logos Biosystems CELENA S Digital Imaging System. Manufacturer specifications and system capabilities were reviewed and compared, including physical configuration and footprint, live-cell imaging capabilities, fluorescence and transmitted-light imaging, sample compatibility, cell-analysis functions, and longitudinal imaging capabilities. Although the ECHO Revolve and CELENA S provide several comparable microscopy functions, neither was identified as providing the complete combination of capabilities required by the laboratory. The EVOS M5000 was therefore determined to meet the laboratory's overall technical and operational requirements. Due to the specialized nature of the laboratory's research and the Government's requirement for the specific combination of a fully integrated microscope configuration, BSC compatibility, live-cell imaging, position tracking, quantitative cell-analysis capabilities, and multi-modal imaging, the Government intends to procure the EVOS M5000 Imaging System on a sole-source basis from Thermo Fisher Scientific. Thermo Fisher Scientific manufactures the EVOS M5000 Imaging System and, based…

Język tego ogłoszenia: English. Tytuł i opis pokazujemy dokładnie tak, jak opublikował je zamawiający.